February  2004, 4(1): 59-80. doi: 10.3934/dcdsb.2004.4.59

From a class of kinetic models to the macroscopic equations for multicellular systems in biology


Department of Mathematics, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy, Italy

Received  January 2003 Revised  July 2003 Published  November 2003

This paper deals with the development of an asymptotic theory for large systems of interacting cells in a vertebrate. Macroscopic diffusion and evolution equations are derived from the microscopic behavior represented by a class of nonlinear kinetic equations obtained as a generalization of the Boltzmann equation in mathematical biology. The analysis shows how the time-scaling plays a crucial role in the derivation of different type of equations. The application, developed in the second part of the paper refers to a model of progressing tumor cells in competition with the immune system. The asymptotic analysis is addressed to derive the mathematical framework of macroscopic equations to describe the evolution of solid tumors in "vivo" or in "vitro" environments.
Citation: N. Bellomo, A. Bellouquid. From a class of kinetic models to the macroscopic equations for multicellular systems in biology. Discrete and Continuous Dynamical Systems - B, 2004, 4 (1) : 59-80. doi: 10.3934/dcdsb.2004.4.59

Weinan E, Jianfeng Lu. Mathematical theory of solids: From quantum mechanics to continuum models. Discrete and Continuous Dynamical Systems, 2014, 34 (12) : 5085-5097. doi: 10.3934/dcds.2014.34.5085


José A. Carrillo, M. R. D’Orsogna, V. Panferov. Double milling in self-propelled swarms from kinetic theory. Kinetic and Related Models, 2009, 2 (2) : 363-378. doi: 10.3934/krm.2009.2.363


Juan Pablo Pinasco, Mauro Rodriguez Cartabia, Nicolas Saintier. Evolutionary game theory in mixed strategies: From microscopic interactions to kinetic equations. Kinetic and Related Models, 2021, 14 (1) : 115-148. doi: 10.3934/krm.2020051


Alexis Arnaudon, So Takao. Networks of coadjoint orbits: From geometric to statistical mechanics. Journal of Geometric Mechanics, 2019, 11 (4) : 447-485. doi: 10.3934/jgm.2019023


Darryl D. Holm, Vakhtang Putkaradze, Cesare Tronci. Collisionless kinetic theory of rolling molecules. Kinetic and Related Models, 2013, 6 (2) : 429-458. doi: 10.3934/krm.2013.6.429


Emmanuel Frénod, Mathieu Lutz. On the Geometrical Gyro-Kinetic theory. Kinetic and Related Models, 2014, 7 (4) : 621-659. doi: 10.3934/krm.2014.7.621


Eduard Feireisl, Šárka Nečasová, Reimund Rautmann, Werner Varnhorn. New developments in mathematical theory of fluid mechanics. Discrete and Continuous Dynamical Systems - S, 2014, 7 (5) : i-ii. doi: 10.3934/dcdss.2014.7.5i


Nicola Bellomo, Francesca Colasuonno, Damián Knopoff, Juan Soler. From a systems theory of sociology to modeling the onset and evolution of criminality. Networks and Heterogeneous Media, 2015, 10 (3) : 421-441. doi: 10.3934/nhm.2015.10.421


Roberto Alicandro, Giuliano Lazzaroni, Mariapia Palombaro. Derivation of a rod theory from lattice systems with interactions beyond nearest neighbours. Networks and Heterogeneous Media, 2018, 13 (1) : 1-26. doi: 10.3934/nhm.2018001


Etienne Bernard, Laurent Desvillettes, Franç cois Golse, Valeria Ricci. A derivation of the Vlasov-Stokes system for aerosol flows from the kinetic theory of binary gas mixtures. Kinetic and Related Models, 2018, 11 (1) : 43-69. doi: 10.3934/krm.2018003


Nicola Bellomo, Abdelghani Bellouquid, Juanjo Nieto, Juan Soler. Modeling chemotaxis from $L^2$--closure moments in kinetic theory of active particles. Discrete and Continuous Dynamical Systems - B, 2013, 18 (4) : 847-863. doi: 10.3934/dcdsb.2013.18.847


Paolo Barbante, Aldo Frezzotti, Livio Gibelli. A kinetic theory description of liquid menisci at the microscale. Kinetic and Related Models, 2015, 8 (2) : 235-254. doi: 10.3934/krm.2015.8.235


Hung-Wen Kuo. Effect of abrupt change of the wall temperature in the kinetic theory. Kinetic and Related Models, 2019, 12 (4) : 765-789. doi: 10.3934/krm.2019030


José Antonio Alcántara, Simone Calogero. On a relativistic Fokker-Planck equation in kinetic theory. Kinetic and Related Models, 2011, 4 (2) : 401-426. doi: 10.3934/krm.2011.4.401


Krešimir Burazin, Marko Vrdoljak. Homogenisation theory for Friedrichs systems. Communications on Pure and Applied Analysis, 2014, 13 (3) : 1017-1044. doi: 10.3934/cpaa.2014.13.1017


Giuseppe Marmo, Giuseppe Morandi, Narasimhaiengar Mukunda. The Hamilton-Jacobi theory and the analogy between classical and quantum mechanics. Journal of Geometric Mechanics, 2009, 1 (3) : 317-355. doi: 10.3934/jgm.2009.1.317


Melvin Leok, Diana Sosa. Dirac structures and Hamilton-Jacobi theory for Lagrangian mechanics on Lie algebroids. Journal of Geometric Mechanics, 2012, 4 (4) : 421-442. doi: 10.3934/jgm.2012.4.421


Julian Braun, Bernd Schmidt. On the passage from atomistic systems to nonlinear elasticity theory for general multi-body potentials with p-growth. Networks and Heterogeneous Media, 2013, 8 (4) : 879-912. doi: 10.3934/nhm.2013.8.879


Katarzyna Grabowska, Janusz Grabowski. Tulczyjew triples: From statics to field theory. Journal of Geometric Mechanics, 2013, 5 (4) : 445-472. doi: 10.3934/jgm.2013.5.445


Manfred Deistler. Singular arma systems: A structure theory. Numerical Algebra, Control and Optimization, 2019, 9 (3) : 383-391. doi: 10.3934/naco.2019025

2020 Impact Factor: 1.327


  • PDF downloads (63)
  • HTML views (0)
  • Cited by (34)

Other articles
by authors

[Back to Top]