Advanced Search
Article Contents
Article Contents

A model of HIV-1 infection with HAART therapy and intracellular delays

Abstract Related Papers Cited by
  • We consider a model of HIV-1 infection with triple drug therapy (HAART) and three delays: the first delay represents the time between the infection and the viral production, the second is associated with the loss of target cells by infection, and the third represents the time for the newly produced virions to become infectious. We show that the incorporation of these delays improves the critical efficacy of the treatment, and destabilizes the infected steady state or leads to an infected steady state with more healthy cells and less infected cells and viruses. Also, we considered the periodic treatment case. We analyze the stability of the viral free steady state and derive an effective strategy for reducing the viral load.
    Mathematics Subject Classification: Primary: 58F15, 58F17; Secondary: 53C35.


    \begin{equation} \\ \end{equation}
  • 加载中

Article Metrics

HTML views() PDF downloads(93) Cited by(0)

Access History

Other Articles By Authors



    DownLoad:  Full-Size Img  PowerPoint