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On the optimality of singular controls for a class of mathematical models for tumor anti-angiogenesis
1. | Department of Mathematics and Statistics, Southern Illinois University Edwardsville, Edwardsville, IL 62026 |
2. | Dept. of Electrical and Systems Engineering, Washington University, St. Louis, Missouri, 63130-4899 |
[1] |
Heinz Schättler, Urszula Ledzewicz, Benjamin Cardwell. Robustness of optimal controls for a class of mathematical models for tumor anti-angiogenesis. Mathematical Biosciences & Engineering, 2011, 8 (2) : 355-369. doi: 10.3934/mbe.2011.8.355 |
[2] |
Nasser Sweilam, Fathalla Rihan, Seham AL-Mekhlafi. A fractional-order delay differential model with optimal control for cancer treatment based on synergy between anti-angiogenic and immune cell therapies. Discrete and Continuous Dynamical Systems - S, 2020, 13 (9) : 2403-2424. doi: 10.3934/dcdss.2020120 |
[3] |
Urszula Ledzewicz, Helmut Maurer, Heinz Schättler. Optimal and suboptimal protocols for a mathematical model for tumor anti-angiogenesis in combination with chemotherapy. Mathematical Biosciences & Engineering, 2011, 8 (2) : 307-323. doi: 10.3934/mbe.2011.8.307 |
[4] |
Zaidong Zhan, Shuping Chen, Wei Wei. A unified theory of maximum principle for continuous and discrete time optimal control problems. Mathematical Control and Related Fields, 2012, 2 (2) : 195-215. doi: 10.3934/mcrf.2012.2.195 |
[5] |
Maciej Leszczyński, Urszula Ledzewicz, Heinz Schättler. Optimal control for a mathematical model for anti-angiogenic treatment with Michaelis-Menten pharmacodynamics. Discrete and Continuous Dynamical Systems - B, 2019, 24 (5) : 2315-2334. doi: 10.3934/dcdsb.2019097 |
[6] |
Hancheng Guo, Jie Xiong. A second-order stochastic maximum principle for generalized mean-field singular control problem. Mathematical Control and Related Fields, 2018, 8 (2) : 451-473. doi: 10.3934/mcrf.2018018 |
[7] |
Ellina Grigorieva, Evgenii Khailov, Andrei Korobeinikov. An optimal control problem in HIV treatment. Conference Publications, 2013, 2013 (special) : 311-322. doi: 10.3934/proc.2013.2013.311 |
[8] |
Antonio Fernández, Pedro L. García. Regular discretizations in optimal control theory. Journal of Geometric Mechanics, 2013, 5 (4) : 415-432. doi: 10.3934/jgm.2013.5.415 |
[9] |
Md. Haider Ali Biswas, Maria do Rosário de Pinho. A nonsmooth maximum principle for optimal control problems with state and mixed constraints - convex case. Conference Publications, 2011, 2011 (Special) : 174-183. doi: 10.3934/proc.2011.2011.174 |
[10] |
Hans Josef Pesch. Carathéodory's royal road of the calculus of variations: Missed exits to the maximum principle of optimal control theory. Numerical Algebra, Control and Optimization, 2013, 3 (1) : 161-173. doi: 10.3934/naco.2013.3.161 |
[11] |
Stefan Doboszczak, Manil T. Mohan, Sivaguru S. Sritharan. Pontryagin maximum principle for the optimal control of linearized compressible navier-stokes equations with state constraints. Evolution Equations and Control Theory, 2022, 11 (2) : 347-371. doi: 10.3934/eect.2020110 |
[12] |
Zhen Wu, Feng Zhang. Maximum principle for discrete-time stochastic optimal control problem and stochastic game. Mathematical Control and Related Fields, 2022, 12 (2) : 475-493. doi: 10.3934/mcrf.2021031 |
[13] |
Evgeny I. Veremey, Vladimir V. Eremeev. SISO H-Optimal synthesis with initially specified structure of control law. Numerical Algebra, Control and Optimization, 2017, 7 (2) : 121-138. doi: 10.3934/naco.2017009 |
[14] |
Christopher Griffin, James Fan. Control problems with vanishing Lie Bracket arising from complete odd circulant evolutionary games. Journal of Dynamics and Games, 2022, 9 (2) : 165-189. doi: 10.3934/jdg.2022002 |
[15] |
Shanjian Tang. A second-order maximum principle for singular optimal stochastic controls. Discrete and Continuous Dynamical Systems - B, 2010, 14 (4) : 1581-1599. doi: 10.3934/dcdsb.2010.14.1581 |
[16] |
Andrea Signori. Penalisation of long treatment time and optimal control of a tumour growth model of Cahn–Hilliard type with singular potential. Discrete and Continuous Dynamical Systems, 2021, 41 (6) : 2519-2542. doi: 10.3934/dcds.2020373 |
[17] |
Maria do Rosário de Pinho, Helmut Maurer, Hasnaa Zidani. Optimal control of normalized SIMR models with vaccination and treatment. Discrete and Continuous Dynamical Systems - B, 2018, 23 (1) : 79-99. doi: 10.3934/dcdsb.2018006 |
[18] |
M. Teresa T. Monteiro, Isabel Espírito Santo, Helena Sofia Rodrigues. An optimal control problem applied to a wastewater treatment plant. Discrete and Continuous Dynamical Systems - S, 2022, 15 (3) : 587-601. doi: 10.3934/dcdss.2021153 |
[19] |
H. O. Fattorini. The maximum principle for linear infinite dimensional control systems with state constraints. Discrete and Continuous Dynamical Systems, 1995, 1 (1) : 77-101. doi: 10.3934/dcds.1995.1.77 |
[20] |
Shaolin Ji, Xiaole Xue. A stochastic maximum principle for linear quadratic problem with nonconvex control domain. Mathematical Control and Related Fields, 2019, 9 (3) : 495-507. doi: 10.3934/mcrf.2019022 |
2021 Impact Factor: 1.497
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