Modeling dynamic changes in type 1 diabetes progression:
Quantifying $\beta$-cell variation after the appearance of
islet-specific autoimmune responses
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Patrick Nelson1, ,
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Noah Smith2, ,
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Stanca Ciupe3, ,
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Weiping Zou4, ,
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Gilbert S. Omenn5, and
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Massimo Pietropaolo6,
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1.
University of Michigan, Department of Mathematics, Center for Computational Medicine and Bioinformatics, 100 Washtenaw Ave, Ann Arbor, 48109-2218
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2.
University of Michigan, Department of Mathematics, 530 Church St., Ann Arbor, 48109
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3.
Duke University, Laboratory of Computational Immunology, Durham, NC 27708
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4.
University of Michigan, Department of Surgery, C558 MSRB II, Ann Arbor, MI 48109
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5.
University of Michigan, Departments of Internal Medicine and Human Genetics, School of Public Health, The Brehm Center for Type 1 Diabetes Research and Analysis, Center for Computational Medicine and Bioinformatics, 100 Washtenaw Ave, Ann Arbor, MI 48109-2219
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6.
University of Michigan, Laboratory of Immunogenetics, Department of Internal Medicine, The Brehm Center for Type 1 Diabetes Research and Analysis, 1500 East Medical Center Drive, Ann Arbor, MI 48109